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In this paper, infrared thermography was employed to study the fatigue process of AZ31B magnesium alloy. In order to eliminate the interference caused by the temperature rise of the fixture, a data processing method was proposed, which is based on a special model to describe the temperature change of the specimen. Based on the temperature data after processing, the temperature evolution indicates that AZ31B magnesium alloy has undergone cyclic hardening during fatigue. Three different temperature indicators were selected to evaluate the