https://crenigacestatinhibitor.....com/anisotropic-mig
Using site-directed mutagenesis and heterologous appearance, we discovered that unantimycin productions tend to be correlated because of the activity of a chorismatase homolog, the nat-hyg5 gene, from a type-I PKS gene group. Biochemical analysis verified that the catalytic activity of Nat-hyg5 produces 3-HBA from chorismate. Finally, we reached discerning production of unantimycins B and C by engineering a chassis host. On the basis of these conclusions, we suggest that unantimycin
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