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Our aim was to explore general practitioners' (GPs) perceptions and experiences of discontinuing antidepressants. A qualitative study using semistructured interviews was undertaken between July 2019 and March 2020. The interviews were transcribed and analysed using a thematic analysis framework. GPs affiliated with a university education and research network for general practice in Ireland. A purposive sample of GPs (n=1. Five themes emerged shared decision-making; personalised therapy; medication-tapering toolkit; health service fac