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BACKGROUND The localization of origins of premature ventricular contraction (PVC) is the key factor for the success of ablation of ventricular arrhythmias. Existing methods rely heavily on manual extraction of PVC beats, which limits their application to the automatic PVC recognition from long-term data recorded by ECG monitors before and during operation. Besides, researches identifying PVC sources in the whole ventricle have not been reported. OBJECTIVE The purpose of this study was to validate the feasibility of localization of orig