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However, HIIT increased the plasma glutathione peroxidase (GSH-Px) activity. Besides, HIIT attenuated the vasoconstriction induced by norepinephrine while has little effect on potassium chloride stimulation. Similarly, the sensitivity of vasorelaxation induced by SNP was upregulated after HIIT. Finally, we identified a decrease of of calcium channel CaV 1.2 on blood vessel in HIIT group. CONCLUSIONS HIIT provides a better control of BP and higher sensitivity to vasorelaxation, which may be related to higher GSH-Px activity and lower Ca