https://www.selleckchem.com/pr....oducts/valaciclovir-
Mild and selective nickel-catalyzed trifluoromethylation and perfluoroalkylation reactions of alkenes were developed to provide fluorinated olefins, including natural products, pharmaceuticals, and variety of synthetic building blocks in good to excellent yields (38 examples). Control experiments, kinetic measurements and in situ EPR studies reveal the importance of radical species and the formation of 1,2-adducts as intermediates.To develop fluorophore-labelled pyridinium-based macromolecular architectures for fluorometric and
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