https://www.selleckchem.com/pr....oducts/rimiducid-ap1
Preclinical research over the past several decades has demonstrated a role for the γ-aminobutyric acidB (GABA receptor in alcohol use disorder (AUD). This chapter offers an examination of preclinical evidence on the role of the GABAB receptor on alcohol-related behaviors with a particular focus on the GABAB receptor agonist baclofen, for which effects have been most extensively studied, and positive allosteric modulators (PAMs) of the GABAB receptor. Studies employing rodent and non-human primate models have shown that activa