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The methods used to build the perfect trees in this article were implemented in the "ROP" R package, archived at https//cran.r-project.org/web/packages/ROP/index.html. Supplementary data are available at Bioinformatics online. Supplementary data are available at Bioinformatics online.The spindle pole body (SP provides microtubule-organizing functions in yeast and duplicates exactly once per cell cycle. The first step in SPB duplication is the half-bridge to bridge conversion via the antiparallel dimerization of the centrin (Cdc31)-bi
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