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How Does Medication For ADHD Work? Stimulants can increase your ability to focus and control impulses by increasing the levels of dopamine and norepinephrine within your brain. They are available in immediate-release (short acting) and extended release tablets. They can be taken once daily in the morning. Nonstimulant medications can help improve the ability to control impulses and attention however they take longer to work. Atomoxetine (Strattera) and guanfacine (Viloxazine) are both in