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Owing to the high reliability and accuracy, it has the capacity to replace ascites puncture with cytologic examination or a more invasive method (laparoscopy, laparotomy) for adequate tumor sampling.Background/aim The development of treatment-related neuroendocrine prostate cancer (t-NEPC) is an increasing clinical concern. The objectives were to clarify the clinical features of t-NEPC. Patients and methods A total of 9 patients with histologically confirmed t-NEPC were reviewed. Results Of these 9 patients, 2 patients were diagnosed wit