https://www.selleckchem.com/pr....oducts/gkt137831.htm
Insulin is a protein macromolecule used to treat diabetes mellitus. Currently, insulin requires multiple daily subcutaneous (SC) injections to control blood sugar in diabetics. Thus, reducing the patients' compliance and adherence to medication as SC route is invasive. Insulin is poorly absorbed through intestinal epithelium because it is a large and hydrophilic molecule, degraded by proteases, and due to the presence of mucosal biophysical barrier. Herein, insulin was encapsulated into different poly(lactic-co-glycolic acid) (PLGA) n