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Importantly, the photo-mediated NO release could be manipulated in living cells and showed promising applications in the treatment of corneal wounds. In addition to delivering NO, the current design enabled the synergistic delivery of NO and other therapeutic payloads by taking advantage of NO release-mediated traceless crosslinking of the vesicles. This journal is © The Royal Society of Chemistry 2020.There is an on-going search for new earth-abundant electrocatalytic materials, suitable for replacing noble-metals as efficient accelera