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4 mg L-1) would erode 35% of the observed oxygen gains. Implementing a nitrogen load reduction of 1.2 × 106 kg year-1 before the century's end would offset the oxygen solubility decline. This overall approach is applicable to areas experiencing warming and continued development that complicate efforts to reign in hypoxia.Pulmonary hypertension (PH) is common in infants with severe bronchopulmonary dysplasia (BPD) and increases the risk of death. The objectives of this preliminary study were to compare responses of pulmonary circulation