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p.). 1dC was also able to permeate to the CNS as shown by in vitro and in vivo models. The maximum brain concentration was close to the IC50 value for acetylcholinesterase inhibition with a relatively slow elimination half-time. 1dC showed an acceptable safety and good pharmacokinetic properties and a multifunctional biological profile.Selective hydrogenation of CO2 to methanol is a "two birds, one stone" technology to mitigate the greenhouse effect and solve the energy demand-supply deficit. Cu-based catalysts can effectively catalyze t
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