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Nonetheless, no studies have already been performed to investigate the possibility usage of probiotics to prevent urogenital infections in sheep. A randomized controlled clinical trial ended up being carried out with 21 one-year-old ewes to build up a model of probiotic infusion in vaginal sponges to be able to study their impact in ewe's vaginal microbiota, general health condition, fertility and prolificity. Synchronization of estrus was based on