https://www.selleckchem.com/pr....oducts/Cediranib.htm
Collectively, our findings reveal the REDD1-mediated stress response as a novel tumor suppressor whose loss defines a RAS mutant tumor subset characterized by reprogramming of lipid metabolism, invasive and metastatic progression, and poor prognosis. This work thus provides new mechanistic and clinically relevant insights into the phenotypic heterogeneity and metabolic rewiring that underlies these common cancers. © 2020 Qiao et al.; Published by Cold Spring Harbor Laboratory Press.Proper nervous system development is required for an