https://www.selleckchem.com/pr....oducts/isa-2011b.htm
The model with clinical and pathological stage fit significantly better than the model with only pathological stage in all men (p = 0.01) and in men diagnosed during the PSA era (p = 0.04). The mutually adjusted model also improved discriminatory ability. In the Johns Hopkins cohort, the model with clinical and pathological stage improved discriminatory ability and fit significantly better overall (p less then 0.0001) and in the PSA era (p less then 0.0001). Conclusions Despite stage migration resulting from widespread PSA screening,
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