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The proposed designs are evaluated in silico, utilising the UVa/Padova T1D simulator, in various mealtime circumstances and compared to the SF and three ∆G-accounting variations recommended in the literary works. An assessment on genuine information, by retrospectively analyzing 218 glycemic traces, can also be performed. All four tested designs performed a lot better than the prevailing practices. LASSO regression with prolonged feature-set including quadratic terms (LASSO ) produced the best