https://www.selleckchem.com/pr....oducts/ttnpb-arotino
Interestingly, DEFB118 decreased the expression levels of critical genes involving in mucosal inflammatory responses (NF-κB, TLR4, IL-1β, and TNF-α) and the apoptosis (caspase3) upon ETEC challenge (P less then 0.05), whereas DEFB118 significantly upregulated the expression of mucosa functional genes such as the mucin1 (MUC1) and sodium-glucose transporter-1 (SGLT-1) in the ETEC-challenged mice (P less then 0.05). These results indicated a novel function of the DEFB118. The anti-inflammatory effect of DEFB118 should mak