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In GOO because of GC, OS is comparable after treatment with upfront resection compared to JT/GT, neoadjuvant therapy, and soon after resection. Upfront JT/GT may allow patients to tolerate chemotherapy and improve selection for gastrectomy.Epidermolysis bullosa (E is a very diverse group of hereditary skin disorders, resulting from mutations in genes encoding proteins of this dermoepidermal junction. Itch (pruritus) the most common signs across all EB subtypes. It occurs in blistered or wounded s