https://micrornaarray.com/repr....oduce-variations-in-
Further, these variations had been examined using MutPred which identified 9 variants becoming extremely pathogenic. ExAC database revealed that every the pathogenic mutations had a small allele frequency significantly less than 0.01. The in silico analysis revealed extremely pathogenic mutations in amelogenin gene which may have a putative connection with amelogenesis imperfecta. These mutations should really be screened in clients for early analysis of susceptibility to AI.Paulowni