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Both acute and chronic SF elevated mRNA and protein amounts of cytokines in peripheral tissues. Alterations in inflammatory reactions mirrored stress-axes activation, with additional corticosterone and norepinephrine in SF mice. 6-OHDA treatment substantially alleviated SF-induced irritation, therefore supplying evidence of SNS regulation of peripheral irritation from SF. outcomes of chronic SF had been more serious than intense SF, and 1 week of recovery from SF adequately alleviate