https://www.selleckchem.com/pr....oducts/epz005687.htm
The de novo construction of axially chiral 3-arylindoles bearing a C(3)-C(aryl) chiral axis has been realized by Pd-catalyzed enantioselective Cacchi reaction between aryl bromides and o-alkynylanilines. The reaction proceeded under mild conditions in high yields and excellent enantioselectivities.Organic-organic interactions play important roles in secondary organic aerosol formation, but the interactions are complex and poorly understood. Here, we use environmental molecular beam experiments combined with molecular dynamics simulati