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Lipoblastoma usually occurs in childhood and is connected with rearrangements for the PLAG1 gene. We provide a patient with an isolated size thought to be a lipoblastoma medically, radiographically, and histologically. The lesion was diagnosed as a PIK3CA-adipose lesion following the muscle was bad for PLAG1 rearrangement and contained a somatic PIK3CA mutation (H1047R). Although PIK3CA alternatives are connected with POSITIVES (PIK3CA-related overgrowth range), this report illustrates a non
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