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Although CHP-1 was recommended to act as a co-chaperone for HSP90, our data indicate that CHP-1 plays an HSP90-independent purpose in managing EGFR trafficking through the ER. © 2020, Haag et al.The essential functions needed for mitotic spindle system and chromosome biorientation and segregation aren't totally understood, despite considerable study. To illuminate the combinations of ingredients most important to align and segregate chromosomes and simultaneously build a bipolar spin