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MiR-148a could inhibit ERK/MAPK signaling pathway through targeting IGF-IR. CONCLUSION MiR-148a plays an anti-tumor role in OSCC and inhibits OSCC progression through suppressing ERK/MAPK pathway via targeting IGF-IR. Copyright 2020 The Author(s).Recently, we designed peptides by sequential substitution of naturally occurring a-amino acid throughout the Ang III peptide sequence with the corresponding b-amino acid. b-amino acid substitution at the proline residue of Ang III (b-Pro7-Ang III) resulted in a highly selective AT2R ligand, de