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BACKGROUND Caffeine, theobromine and theophylline are main purine alkaloid in tea. Theophylline could be the downstream metabolite also it remains at an extremely low-level in Camellia sinensis. Inside our previous research, Aspergillus sydowii could transform caffeine into theophylline in solid-state fermentation of pu-erh beverage through N-demethylation. In this study, tea-derived fungi caused theophylline degradation in the solid-state fermentation. The purpose of this st