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genes, which can act as potential targets for the treatment of OSCC patients with cisplatin resistance. Copyright © 2020 Wu, Chen, Li, Shen, Ye, Zhang, Chen and Liu.The prevalence of tickborne diseases worldwide is increasing virtually unchecked due to the lack of effective control strategies. The transmission dynamics of tickborne pathogens are influenced by the tick microbiome, tick co-infection with other pathogens, and environmental features. Understanding this complex system could lead to new strategies for pathogen control, but w