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The resulting nanocomposites exhibit a significantly reduced permeability as compared to unfilled PLA and an improved young modulus and toughness at the detriment of ductility.Complement C1q is a multifunctional protein able to sense pathogens and immune molecules such as immunoglobulins and pentraxins, and to trigger the classical complement pathway through activation of its two associated proteases, C1r and C1s. C1q is a multimeric protein composed of three homologous yet distinct polypeptide chains A, B, and C, each composed of an N-ter