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Response to altrenogest was not associated with (p=.31) or able to predict a beneficial response to surgery (OR=5.5; 95% CI=0.38-78.57; p=.21). Response to altrenogest in elective cases may not predict behavioral outcome with ovariectomy. Occasional estrus-like behavior in mares postoperatively was not problematic for any owners. Bilateral ovariectomy is a viable treatment option for owners seeking to alleviate undesirable behavior in mares. This study should aid veterinarians and horse owners in case selection for bilateral ovariectomy

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