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The accumulation ratios after multiple administrations were 1.3 and 1.6 for tiotropium and olodaterol in Chinese patients. Tio+Olo FDC was well-tolerated; all AEs were mild. Tio+Olo FDC (5 μg/5μg) was rapidly absorbed and had a good safety profile in Chinese patients with COPD. Tio + Olo FDC (5 μg/5 μg) was rapidly absorbed and had a good safety profile in Chinese patients with COPD.Currently, renal denervation (RDN) has proven its overall procedural and renal safety in registries and trials. Available data, suggest that vascular complica

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