https://www.selleckchem.com/pr....oducts/caerulein.htm
The calcium-sensing receptor (CaSR) is essential to maintain a stable calcium concentration in serum. Spermatozoa are exposed to immense changes in concentrations of CaSR ligands such as calcium, magnesium, and spermine during epididymal maturation, in the ejaculate, and in the female reproductive environment. However, the role of CaSR in human spermatozoa is unknown. This work aimed to investigate the role of CaSR in human spermatozoa. We identified CaSR in human spermatozoa and characterized the response to CaSR agonists on intracel