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The article presents the results of an experimental study on the knee joint structural changes and morphometric evaluation of articular cartilage with the injections of platelet rich plasma (PRP) and bone marrow aspirate concentrate (BMAC). Cartilage defect, anterior cruciate ligament intersection and medial meniscus resection were performed for the induction of osteoarthritis in rabbits. After 28 days, 0.9% NaCl, PRP or BMAC was administered intra-articularly; 0.9% NaCl or PRP was injected intra-articularly within 14 days. After 2 months,
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