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22; 95% CI, 1.69-10.51) were independent factors of polymicrobial SA-BSI. In comparison with monomicrobial SA-BSI, patients with polymicrobial SA-BSI had longer length of ICU stay [median days, 23(6.25,49.25) vs. 0(0,12), p less then 0.01] and hospital stay [median days, 50(21.75,85.75) vs. 28(15,49), p less then 0.01], and showed a higher 28-day mortality (29.6% vs. 15.3%, p = 0.01). Conclusions Burn injury, blood transfusion, mechanical ventilation, the length of prior hospital stay, and pneumonia as a primary site of infection are i