https://www.selleckchem.com/pr....oducts/talabostat.ht
Rheumatoid arthritis (RA) can be initiated and driven by immune responses to multiple antigenic epitopes including those in cartilage proteoglycan (PG, aggrecan) and type II collagen. RA is driven by T helper 1 (Th1) or Th17 pro-inflammatory T cell responses. LEAPS (Ligand Epitope Antigen Presentation System) DerG peptide conjugate vaccines were prepared using epitopes from PG that elicit immune responses in RA patients epitope PG70 (DerG-PG70, also designated CEL-400 and the citrullinated form of another epitope (PG275Cit). The LE
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