https://www.selleckchem.com/pr....oducts/k-ras-g12c-in
The control of skin permeability to specific substances (e.g., medications, vitamins, and nutrients) through stratum corneum is a challenge. Iontophoresis is an option in spite of the lack of a detailed understanding of the underlying molecular mechanism. In the present work, the simulations concerning application of an external continuous electric field to stratum corneum, in a range of low intensity (0-24 mV nm-1), were carried out using the coarse-grained molecular dynamics approach. Using a set of random seed replicas
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