https://www.selleckchem.com/pr....oducts/ll37-human.ht
The p53 protein and its post-translational modifications are distinctly expressed in various normal cell types and malignant cells and are usually detected by immunohistochemistry and flow cytometry in contemporary diagnostics. Here, we describe an approach for simultaneous multiparameter detection of p53, its post-translational modifications and p53 pathway-related signaling proteins in single cells using mass cytometry. We conjugated p53-specific antibodies to metal tags for detection by mass cytometry, allowing the detection of pr
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