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Ellner et al. (202 state that identifying the mechanisms producing positive invasion growth rates (IGR) is useful in characterising species persistence. We agree about the importance of the sign of IGR as a binary indicator of persistence, but question whether its magnitude provides much information once the sign is given.Glioma is a common type of malignant brain tumour with high mortality and relapse rate. However, the molecular mechanisms of glioma development have not been clarified. Differentially expressed genes in normal brain tis
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