https://www.selleckchem.com/products/LBH-589.html
Error correction is a fundamental preprocessing step in many NGS pipelines, in particular for de novo genome assembly. However, existing error correction methods either suffer from high false positive rates since they break reads into independent k-mers or do not scale efficiently to large amounts of sequencing reads and complex genomes. We present CARE - an alignment-based scalable error correction algorithm for Illumina data using the concept of minhashing. Minhashing allows for efficient similarity search within large sequencing read