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(1) To confirm the reliability of a Japanese version of the Youth Quality of Life Instrument-Facial Differences Module (YQOL-FD); (2) to assess the quality of life (QoL) related to facial difference in Japanese youths with cleft lip and/or palate (CL/P) using this instrument; and (3) to examine the QoL differences according to age, sex, and cleft type. A cross-sectional study. Japanese youths with CL/P were recruited through our hospital and asked to complete the YQOL-FD. Sixty-nine Japanese youths (age, 11-18 years) with CL/P. The domain

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