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e faster and reached a higher peak. Copeptin levels did not change significantly. Registration URL https//www.clinicaltrials.gov; Unique identifier NCT03203057. This study is the first to report the early-release kinetics of cTn concentrations after different durations of experimental coronary balloon occlusion in humans. All assays detected a cTn increase after only 30 s of ischemia. hs-cTnI (Siemens) rose faster and reached a higher peak. Copeptin levels did not change significantly. Registration URL https//www.clinicaltrials.gov; Uni