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Overall survival was 11.4 months (±8.6). Median GFAP value was 70% (range, 5-100%). The ROC curve showed the clinically relevant cut-off for GFAP at 75% (area under the curve 0.691). Accordingly, GB patients with GFAP ≥75% presented poorer survival on Kaplan-Meier survival estimation (p=0.021). Multivariate analysis adjusted for age, extent of resection, preoperative Karnofsky performance status scale, IDH1 mutation and MGMT methylation status confirmed the independent predictive value of GFAP ≥75% for overall survival (p=0.032). Finally,

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