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ce 3.Study design Meta-analysis. Objective To evaluate the efficacy and safety of total disc replacement (TDR) and anterior cervical discectomy and fusion for treating cervical degenerative diseases. Summary of background data Anterior cervical discectomy and fusion (ACDF) has been the traditional gold standard surgery for cervical degenerative diseases. Methods Clinical databases including PubMed, MEDLINE, Cochrane and Clinical Trials.gov were searched. Review Manager 5.1 software and Stata 11.1 were used to analyze clinical data. Dichot
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