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02, 95%CI -0.05-0.01, P = .15, I2 = 74%) and postoperative cognitive dysfunction (MD -0.08, 95% CI -0.14 -0.01, P = .02, I2 = 94%). Bispectral index monitoring of propofol closed-loop target-controlled infusion system can reduce the amount of propofol, reduce the incidence of adverse reactions such as hypertensive or hypotension and postoperative cognitive dysfunction. Bispectral index monitoring of propofol closed-loop target-controlled infusion system can reduce the amount of propofol, reduce the incidence of adverse reactions such

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