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It contains four main saponins which are its significant bioactive substances. These saponins tend to be Paris saponin we, II, VI and VII (PSI, PSII, PSVI and PSVII, correspondingly). So far, the investigation using HUVEC cells to evaluate the anti-angiogenic activity of four saponins is blank. The goal of this study was to assess the anti-angiogenic properties (also known as angiotoxicity) associated with the four saponins in Rhizoma Paris on vascular endothelial cells-HUVEC cells,
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