https://www.selleckchem.com/pr....oducts/Gefitinib.htm
In this review we discuss the evidence implicating the MPC as an important, perhaps causal, mediator of heart failure progression.Ubiquitination is an essential post-translational modification that regulates most cellular processes. The assembly of ubiquitin into polymeric chains by E3 ubiquitin ligases underlies the pleiotropic functions ubiquitin chains regulate. Ubiquitin chains assembled via the N-terminal methionine, termed Met1-linked ubiquitin chains or linear ubiquitin chains, have emerged as essential signalling scaffolds tha