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https://www.selleckchem.com/pr....oducts/l-ornithine-l
NAFLD is a growing public health burden. However, the pathogenesis of NAFLD has not yet been fully elucidated and the importance of genetic factors has only recently been appreciated. Genomic studies have revealed a strong association between NAFLD progression and the I148M variant in PNPLA3. Nonetheless, very little is known about the mechanisms by which this gene and its variants can influence disease development. In order to investigate these mechanisms, we have developed an in vitro model that takes advantage of the

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