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In addition, three regions within each human surgical PDAC specimen were assessed tumor, which had both the highest Young's modulus (YM 40 kPa) and collagen density (PSR 40 %); non-neoplastic adjacent pancreas, which had the lowest Young's modulus (YM less then 15 kPa) and collagen density (PSR less then 10%) and a transitional peri-lesional region between the tumor and non-neoplastic pancreas with an intermediate value of measured Young's modulus (15 kPa less then YM less then 40 kPa) and collagen density (15% less then PSR

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