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https://www.selleckchem.com/products/CX-3543.html
BACKGROUND Frailty is the loss of ability to withstand a physiological stressor and is associated with multiple adverse outcomes in older people. Trials to prevent or ameliorate frailty are in their infancy. A range of different outcome measures have been proposed, but current measures require either large sample sizes, long follow-up, or do not directly measure the construct of frailty. METHODS We propose a composite outcome for frailty prevention trials, comprising progression to the frail state, death, or being too unwell to continue

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