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Some biologists and philosophers of biology claim selection can "create" novel traits. Others claim creativity is to be found only in development. I here endorse the former claim, but take seriously and address the concerns that underlie the latter. My discussion of these issues is informed by recent work that champions the "return of the organism" to mainstream evolutionary biology, and I suggest how population and organismal perspectives on trait origins can be reconciled. 8-Hydroxydeoxyguanosine (8-OHdG) is an indicator of oxidative
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